Position Title:  Scientist Regulatory Toxicology

Scientist Regulatory Toxicology – Neuchatel, Switzerland

Be a part of a revolutionary change.

At PMI, we’ve chosen to do something incredible. We’re totally transforming our business, and building our future on smoke-free products.

With huge change, comes huge opportunity. So, wherever you join us, you’ll enjoy the freedom to dream up and deliver better, brighter solutions and the space to move your career forward in endlessly different directions.

It’s so rare in R&D that everything aligns to create the ideal conditions for outstanding work. Right now, at PMI, that’s exactly what’s happening. R&D is the driving force for our bold new vision: to replace cigarettes with a revolutionary portfolio of alternative products.

Join us and you’ll have the resources, support and technology you need to break new ground and see ideas come to life. You’ll be surrounded by some of the brightest scientists in their fields, with fast access to subject experts and commercial decision-makers.

If you’re creative, courageous and ready to take risks, you can make a huge impact and propel your career in an endless number of directions. Ultimately, by delivering our smoke-free and beyond nicotine future

Your ‘day to day’

As a Scientist Regulatory Toxicology, you will be responsible to apply well-defined methodologies and work procedures to perform/elaborate analyses/studies and technical activities to support the laboratory activities within the Non-clinical Science (NCS) Laboratories & Operations organization. You will carry out activities in accordance with Good Laboratory Practice (GLP) according to the RS 813.112.1 Ordonnance sur les bonnes pratiques de laboratoire (OBPL) du 18 mai 2005 (Etat le 12 juillet 2005), ISO/IEC 17025 General requirements for the competence of testing and calibration laboratories and the respective PMI procedures. You will conduct methodologies and systems development and validation activities of low to high complexity and write related scientific documents, by collaborating with external functions such as Quality Assurance (QA). You will be expected to apply problem-solving techniques and may suggest improvements for methodologies, processes, systems, and/or equipment.

More specifically, you'll

• Ensure timely end-to-end execution of all required activities to complete nonclinical toxicological in vitro assessment.
• Design, plan, and oversee experiment execution based on business demand in both regulatory and exploratory areas.
• Collect, analyze (when required), interpret experimental data, and draw data-driven conclusions.
• Support the line manager by overseeing training and coaching lab technicians.
• Prepare data reports according to business needs and present scientific findings to team members and internal stakeholders.
• Provide contribution to write validation/qualification documents for both methodologies and assets.
• Stay updated with the latest scientific advancements and techniques in the corresponding scientific fields and propose innovative approaches to expand the lab portfolio with improved solutions.
• Support the line manager in lab organization, quality topics, data release and people management activities as per business requirement.
• Perform duties in accordance with Good Laboratory Practices (GLP) principles, ISO 17025 standards and the respective PMI procedures, as required, and ensure that processes, documents, and activities align with the respective quality requirements. When required, author work instructions and train colleagues. Adhere to all EHS rules, policies, and procedures.

Who we’re looking for

• Master's degree or PhD Degree in biological science, or equivalent experience.
• Minimum 5 years’ experience in the laboratory environment, conducting in vitro genetic toxicology studies (e.g., in vitro micronucleus assay according to OECD TG 487 by flow cytometry).
• Experience in BSL-2 laboratory.
• Experience with GLP and ISO 17025 quality standards.
• Good MS Office skills and experience with LIMS.
• Fluency in English, both written and spoken is required.

What we offer

Our success depends on the people who come to work every single day with a sense of purpose and an appetite for progress.

Join PMI and you too can:

• Seize the freedom to define your future and ours. We’ll empower you to take risks, experiment, and explore.
• Be part of an inclusive, diverse culture, where everyone’s contribution is respected; collaborate with some of the world’s best people and feel like you belong.
• Pursue your ambitions and develop your skills with a global business – our staggering size and scale provides endless opportunities to progress.
• Take pride in delivering our promise to society: a smoke-free future.