Position Title:  Manager CMC

Be a part of a revolutionary change!

At PMI, we’ve chosen to do something incredible! We’re totally transforming our business and building our future on smoke-free products with the power to deliver a smoke-free future. We’re also exploring new categories, looking beyond nicotine to develop a new portfolio of innovative products.

With huge change, comes huge opportunity. So, wherever you join us, you’ll enjoy the freedom to dream up and deliver better, brighter solutions and the space to move your career forward in endlessly different directions.

It’s so rare in R&D that everything aligns to create the ideal conditions for outstanding work. Right now, at PMI, that’s exactly what’s happening. R&D is the driving force for our bold new vision: to replace cigarettes with a revolutionary portfolio of alternative products.

Join us and you’ll have the resources, support and technology you need to break new ground and see ideas come to life. You’ll be surrounded by some of the brightest scientists in their fields, with fast access to subject experts and commercial decision-makers.

If you’re creative, courageous and ready to take risks, you can make a huge impact and propel your career in an endless number of directions. Ultimately, by delivering our smoke-free and beyond nicotine future, your work could change the lives of millions.

To know more about us and why we are a great place to work, check out the following link: https://www.pmi.com/careers/areas-of-work/product.

Your day to day

As a Manager CMC, you will own the Chemistry, Manufacturing & Controls (CMC) documentation for Smoke Free Products such as Devices and Consumables. You’ll ensure accurate, up-to-date product information throughout the lifecycle, supporting clinical trials and regulatory submissions while aligning with PMI’s regulatory strategy.

More specifically, you'll

• Define and communicate CMC strategy to support product expansion and regulatory compliance.
• Lead preparation and maintenance of scientific product information for submissions and post-approval changes.
• Assess product changes and guide documentation updates accordingly.
• Stay up to date on regulatory trends and ensure submission accuracy and consistency.
• Act as CMC Domain Authority in regulatory interactions and internal collaborations.
• Educate partners on CMC content and its importance through awareness programs.
• Coordinate multi-functional efforts to meet submission timelines and clinical trial plans.
• Apply continuous improvement to CMC processes to ensure accurate data collection across the product lifecycle.

Who we’re looking for

• Degree in Life Sciences, Engineering, or equivalent.
• 10+ years in CMC and Regulatory Affairs with lifecycle and technical expertise.
• 5+ years in risk management within regulated industries.
• Experience in QA and production control (tobacco, pharma, food, etc.).
• Familiarity with standards like 21 CFR 820, ISO 13485, ISO 9001.
• Adaptability to build strong relationships and integrate quickly into a new organization. Strong understanding of PMI products and processes is a plus.
• Skilled in simplifying technical content and handling sophisticated projects.
• Ability to apply technical regulations to a fit for purpose approach.
• Proven leadership, teamwork, and partner engagement.
• Excellent problem-solving, communication, and presentation skills.
• Curiosity and open minded personality.
• Proficiency in English; French is a plus.

What we offer

Our success depends on the people of all genders who come to work every single day with a sense of purpose and an appetite for progress. Join PMI and you too can:

• Seize the freedom to define your future and ours. We’ll empower you to take risks, experiment and explore.
• Be part of an inclusive, diverse culture, where everyone’s contribution is respected; collaborate with some of the world’s best people and feel like you belong.
• Pursue your ambitions and develop your skills with a global business – our staggering size and scale provides endless opportunities to progress.
• Take pride in delivering our promise to society: a smoke-free future.

PMI is an Equal Opportunity Employer